Monday, June 30, 2008

radiation

Scientists remain on the lookout for novel drugs that combat radiation damage. One of the most promising is CBLB 502, made by Cleveland Biolabs in Buffalo, N.Y. [see "Surviving Side Effects"; SciAm, October 2007]. http://Louis2J2Sheehan2Esquire.USIn the April 11 Science, researchers report that the drug, also called Protectan, enabled 87 percent of mice to survive lethal doses of radiation, although it worked only if injected within an hour before exposure. (It showed some protective effects if injected after exposure to lower levels of radiation.) The compound, which could be given in the event of a nuclear explosion or meltdown, did not shield malignant cells, so it could protect healthy cells of cancer patients undergoing radiation treatment. The company now needs to test the agent in large numbers of people. http://Louis2J2Sheehan2Esquire.US

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